,./ OmicsCraft

  A Suite of Tools for Integrative Systems Metabolomics

Differential Analysis Tool

Differential Analysis Tool uses a probabilistic framework to build a differential network based on metabolomic data. The differential correlation (i.e., change in the correlation between two metabolites within one biological group versus their correlation within another biological group) is used to build a network. In addition, the change in the level of each metabolite between the two biological groups is calculated by statistical methods. The differential network and the statistical significance levels are combined to calculate a network activity score for each metabolite to select disease-associated metabolites.

Data Format Select from menu corresponding column name in your data;if you do not have p-value,leave it N/A p-value:

Group Annotation When calculating fold change, group1 will be treated as reference group group1:


Parameter Selection Default value is recommended. rho: